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The Gut-Brain Connection: 6 Ways Your Intestinal Microbiome Plays a Role in Anorexia and Bulimia

by | Mar 18, 2025

Microbiome

The human gut is home to trillions of bacteria, collectively known as the gut microbiome. These tiny organisms do more than just help with digestion—they communicate directly with the brain, influencing mood, cravings, and even behaviors around food. Emerging research suggests that imbalances in the gut microbiome may play a role in the development and persistence of eating disorders, particularly anorexia nervosa and bulimia nervosa.

How the Gut Microbiome Affects Anorexia and Bulimia

  1. Gut Bacteria and Cravings Certain bacteria in our intestines influence the types of food we crave. For example, an overgrowth of specific bacteria that thrive on sugar may increase sugar cravings (Alcock et al., 2014). In individuals with anorexia and bulimia, disruptions in gut bacteria may contribute to an altered perception of hunger and satiety, making recovery more challenging.
  2. The Gut-Brain Axis and Mental Health The gut produces neurotransmitters such as serotonin and dopamine, which play essential roles in mood regulation. About 90% of serotonin—the “feel-good” neurotransmitter—is produced in the gut (Carabotti et al., 2015). In individuals with anorexia and bulimia, imbalances in gut bacteria can lead to reduced serotonin production, exacerbating anxiety, depression, and obsessive food-related thoughts.

3.Inflammation and Stress Responses Imbalances in gut bacteria can lead to chronic low-grade inflammation, which has been linked to heightened stress responses and emotional dysregulation (Clarke et al., 2013). This may worsen restrictive eating patterns in anorexia and binge-purge cycles in bulimia, as both disorders often involve stress-driven coping mechanisms.

4. Improving Your Microbiome for Better Recovery

The good news? You can actively support your gut health, which may, in turn, help regulate appetite, cravings, and mood.

1. Prioritize Fiber-Rich Foods

Prebiotic fibers found in fruits, vegetables, legumes, and whole grains feed beneficial gut bacteria, helping to restore balance. Some excellent sources include:

  • Bananas
  • Onions and garlic
  • Asparagus
  • Oats

2. Incorporate Probiotics and Fermented Foods

Probiotics introduce beneficial bacteria into the gut. Adding more probiotic-rich foods to your diet can enhance microbial diversity:

  • Yogurt (with live cultures)
  • Kefir
  • Sauerkraut
  • Kimchi

3. Include Healthy Fats and Omega-3s

Healthy fats support gut health and reduce inflammation. Omega-3 fatty acids, in particular, promote beneficial bacterial diversity and have anti-inflammatory properties:

  • Fatty fish (salmon, sardines, mackerel)
  • Chia seeds
  • Flaxseeds
  • Walnuts

4. Eat Polyphenol-Rich Foods

Polyphenols are plant compounds that act as fuel for good gut bacteria and have been linked to improved mental health:

  • Dark chocolate (at least 70% cocoa)
  • Green tea
  • Berries (blueberries, strawberries, blackberries)
  • Olive oil

5. Reduce Ultra-Processed Foods and Artificial Sweeteners

Highly processed foods can promote harmful gut bacteria growth. Artificial sweeteners, like aspartame and sucralose, have been shown to negatively alter the gut microbiome and may increase cravings (Suez et al., 2014).

6. Manage Stress and Sleep

Chronic stress and poor sleep quality disrupt the microbiome and contribute to anxiety around food choices. Practices such as mindfulness, deep breathing, and consistent sleep hygiene can support both gut health and mental well-being.

The Takeaway

Your gut microbiome plays a significant role in shaping your relationship with food. While gut health alone cannot “cure” anorexia or bulimia, optimizing your microbiome may improve mood, regulate appetite, and create a foundation for a healthier recovery journey.

By making small, sustainable changes to your diet and lifestyle, you can support both your gut and your mind—bringing you one step closer to a more balanced and intuitive way of eating. Please reach out to us a www.nicrd.com or email us at admin@nicrd.com with any further questions.


References:

  • Alcock, J., Maley, C. C., & Aktipis, C. A. (2014). Is eating behavior manipulated by the gastrointestinal microbiota? Evolutionary pressures and potential mechanisms. BioEssays, 36(10), 940-949.
  • Carabotti, M., Scirocco, A., Maselli, M. A., & Severi, C. (2015). The gut-brain axis: Interactions between enteric microbiota, central and enteric nervous systems. Annals of Gastroenterology, 28(2), 203-209.
  • Clarke, G., Grenham, S., Scully, P., Fitzgerald, P., Moloney, R. D., Shanahan, F., Dinan, T. G., & Cryan, J. F. (2013). The microbiome-gut-brain axis during early life regulates the hippocampal serotonergic system in a sex-dependent manner. Molecular Psychiatry, 18(6), 666-673.
  • Suez, J., Korem, T., Zilberman-Schapira, G., Segal, E., & Elinav, E. (2014). Artificial sweeteners induce glucose intolerance by altering the gut microbiota. Nature, 514(7521), 181-186.
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